She began her career as a music director with her father's production Unnaipol Oruvan and had her own music band and album. Her cousins are actresses Anu Hasan and Suhasini Maniratnam.
Haasan studied at Lady Andal Venkatasubba Rao school in Chennai and moved to Mumbai to study psychology at St. Haasan's first appearance in a feature film was a cameo role as the daughter of Vallabhbhai Patel in the Tamil-Hindi bilingual Hey Ram, based on a murder attempt on Mahatma Gandhi, directed by her father Kamal Haasan.
The film, however, became a commercial failure at the box office, and the film failed to capitalize on a hefty promotional campaign that had been undertaken.
Shruti Haasan has recently been honored with life membership of the International Film And Television Club of Asian Academy of Film & Television by Sandeep Marwah.
Shruti Haasan was next seen in Aishwarya Dhanush's directorial debut 3, a romantic drama film co-starring Dhanush.
After rejecting prominent film offers, most notably the lead role in Venkat Prabhu's Saroja, reports suggested in late 2007 that Haasan was set to make her actual acting debut in 2008 with a film opposite Madhavan, directed by Nishikanth Kamat.
Reviewers were critical of her performance with Rajeev Masand of IBN stating that she delivers "dialogues with deadpan expressions", while another critic added that she is perhaps "synthetic and fails to impress".
As a child artist, she sang in films and appeared in a guest role in her father's Hey Ram (2000), before making her adult acting debut in the 2009 Bollywood film, the drama thriller film Luck.
She later went on to win critical acclaim for her role in the Walt Disney fantasy film in Telugu, Anaganaga O Dheerudu (2011), Oh My Friend (2011) and her Tamil debut 7aum Arivu (2011).
After several successful films such as Gabbar Singh (2012), Vedalam (2015), Srimanthudu (2015) and Singam 3 (2017), she established herself as one of the leading contemporary actresses in Tamil and Telugu cinema.
Alongside appearing in Tamil and Telugu films, she has also appeared in several commercially successful Hindi films, including Ramaiya Vastavaiya (2013), Gabbar Is Back (2015) and Welcome Back (2015).
The film opened to mixed reviews, but became commercially successful.